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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f10ccd777c3dfc192dcbaf0260bc11ccd50f131f21ed5d1e280edd8842029df8' 
  AND token = '1kFWv77uV4T12TE+FXghQsIdGM4sh5UZ0lnMbpvazik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}