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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '756be2f8b9bb9c1fb888c911fbb33221d7b15385b7d55d4320a4f8328ca50753' 
  AND token = 'bHbUDaXOWjXErVfE14aNUgfPoraCPhbbsFhP/vbP6Sk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}