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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a519882e64633607c23826b4e49929c95af176512f11daa026f2492b155e560b' 
  AND token = 'x5V+LTEpo60kOLgp6OQf9avSJRlW2CoDKt/HD1PgSWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}