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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b65d5a0c170e1bbdf849e4a4c2e7fd91c66bfd3a0803fcfdedb20d783f5e3b' 
  AND token = 'K8AgJim5InJrov853lxatr0GTFFEtF31qCeZrHpGbS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}