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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e305e5b9eed208ba40b56f17199b875d763498752794c12725656caef3a8f11' 
  AND token = 'dntGvisHeV2m5HS1r2pcYCG/PycUHxIpnmLEnpF9QV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}