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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '535a21c251f36ab81a1c43e13eceead400c99669041f33d015f26c3bac12e74c' 
  AND token = 'KAIrZtd/i5IB1+8pXPcPYa1dpznu0Tc4vCmgV6kRyZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}