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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaf01dffdea1c02973aa4bed2981da26faa5e3abedef7f6c6f4b4b1400594a81' 
  AND token = 'SDi14xIS8SpQHOk07LtKP6MbuGFtNj0HVKaSM9x3Bmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}