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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de6738db90b4184bbe79655e6d0304ff81778b0f5b9a2cea177b0b439bf956c5' 
  AND token = 'lU3+gMvEAIOFCExHH3r4itQ0PXX6V/axBOms8HhN4hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}