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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2882408be79949da42c320e6c43a34acb2350d8c843d67211ae9b7420df14eb' 
  AND token = 'PvCQoMoXC6KvVMr1U4tWpWqJLSABsEz+M4jwkfR38oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}