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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '478a96e460fe8540b48c55818315773d7f2a159a8c903b20ca1e17a1c34274b7' 
  AND token = 'okIJZt3gXk4puXyECHkehd+COGrTXOd/M1CnWudk7ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}