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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42630d29093e51d92e8680b5cff6b9fc0cff917afe83fdad162c3bc98c0a1c13' 
  AND token = 'Pf+ZnsY89BRCIRftLfk7u7cnq2qSzpZOZ57ikGWUM8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}