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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccfbe21c8d74fa2dfd35f44edace4703a47f9a7d072c49494c9b41b4d3f474a8' 
  AND token = 'ic4mXuxZfcGYiXs79JxGrB0JOu6+iLVnKWxZX3KA1O8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}