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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '251cdcba2d05433096ba1ea657bec0b8a52af5736bb192f1af1897c8d2317b89' 
  AND token = '3LdKoM+vDOaj3lZUN+thy5Q0HDGPNvJeuPr2B0bWmL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}