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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91e42637999d482777e314c63704ad252a3c0afd5aae759289655b4296896130' 
  AND token = '92q6loVKokJ4UHtwNcyWMApw26zuaECY3QfjAupEeVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}