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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2906be7bd90733627011e5cef5a7e3b981795204d80fcad5b2fb8faf525edfe' 
  AND token = 's16wrKUzYThueRJiPkDtM2sQul030OBSs0Dk5P/kehA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}