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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ad2341f619118893252a40d8b7c5f2a98daee5a14c702a2dbf32985b6d9c2d4' 
  AND token = 'Ld1xovsOsJ2gFA+n7rGHeboLhg58zlL4kXl553TJYgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}