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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6bd75a3f22b15cd831b1a2dd22328db814c06e251538e3c062865ad6faf96af' 
  AND token = 'GRIxKdpw0WOOr9O/5YfvJuF6fo7FG/cUVN7la/QhPJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}