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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8f56df5e41d254aef9ec53a59896b2d4a34c41da926b993375593f1689daa07' 
  AND token = 'GOhw/F6xWLRAA3f6uqpTFWmPnEDs/wj39xJg3+ydLi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}