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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6c428d5975fc4c075b0011f81f83b01f6c62b02c1c8819d43f7a3bcd51864b5' 
  AND token = 'Msy8Jf44VF7iEnmwKui82q+YSGdbnPysqBH8d5KO6lU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}