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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '258f20f51f3e362e5e0a992de33927758987af1b41774535f9bbc034a75703b9' 
  AND token = 'ny6cV86fy3L+UybfyjlAsbphDJ2e1CMaHLWMw75cMcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}