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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '93acfdb4de117f4651f0561cf966252ac60e0413a5a3acbf3e12b6a2d8016276' 
  AND token = 'Ay6C4A3Or+mE7pobYA63Aztwpx0ZbOxH0Pu+/qLzl00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}