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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffd1beb3cc4f64a8fcf1487a50e724731d729ec21cfdb251372cb4af7bcbe13a' 
  AND token = '8q/0H+gtn6n8NScJmPit1kX9IFz1bAPkpeMql/XUPsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}