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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a0e90d348d2b2568fedb395a3fbba4c477165c91f3bc8f5ef66b4e9401da3df' 
  AND token = 'hM3IEMkwDRpF2VvuaZ6dUawcrrllqXZDbxCt48eFZBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}