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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2de4231b42898b5d321f5e75f43ee4f72f877de1f2eed7e16121f639f5eb617' 
  AND token = 'dIqS9pbDuBKvlR6TblqGbtLPLIlsz3SJnpTqGVg7R8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}