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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d807a68c1a09cadd468166d4b31a8aa34c2f6d7c8eb392bea69ab0eb068374c' 
  AND token = 'Hcib06aSBtfc3krU/H6GZu8qwVuq7Z3kdWpNiy/pcqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}