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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5166c6ff194df55aadd1ee316294991bb042d979bc4d7a622d60d3416778ad59' 
  AND token = 'wU83iMbcwIrX9eh+xvrvv9Sbdgsc5EaXwEB/Oo5yYVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}