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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a590b05f33fef206b5bb9ea4f7bc7b592923153dff0dc9cb929ffa50b98fee61' 
  AND token = 'XdWj6/+3E4lqjzzsUL3dVJAabUUcs9sYBokN1GEdUD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}