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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e188e3c16a54ccf3bf29faa0c5782bb84ccd8e4caedf628636622d33ce0bda48' 
  AND token = 'HgayBo1kHJtrkkftMXlxNpRB98B3koJgActP/3jUWDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}