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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1df80745a0a42a6e4611daaba9c69ee8dc8d9bdf14ac79100b3afd2238b8f778' 
  AND token = 'PGBokFO7+9LzDxmSTkMem0djC3KcThodej22/verxrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}