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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1af4fb4b0e8108583d152c2952ca7778072015b0069e3c21ba8a6138e5d486c' 
  AND token = 'cRW0eTN34Z20sAvlMrdwxa5yEjmTDg3Ahx2fDETdmKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}