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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c723c5ed7606d1e5ef8f7f4bb8b6e39b06eb322f58424544361a164a46a9065d' 
  AND token = 'gRnxqAtgfEm3iak0l3KQDSMFUE2vLnRx1EV+jqLN8Nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}