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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5b006f3f990c1bd0fbc91b7408ce495a42fc6b001a84bc66855ec600f6d3c0d' 
  AND token = '1OMf6GVmMj3xNxsSOinxP2GfaShzhbZFe2i4vl3Z8Qg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}