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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '043fe8104ca8229a11cceee823e9cd01ac1e407804fa7310844119e4b902262c' 
  AND token = 'uHq61Zm0goYhWICGigZ6wFoH//paEFMgJtX4mYvL2+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}