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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d4017a5e1a83b21928d50375384b587d3fd6967046c11d43f1d70a914a63265' 
  AND token = '5wnWvPwYMm5P/X2Q7S17kipLhdKoEuygI1wiROeVe9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}