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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e686858efdd5a363885b868472d9d2911701fe3e3bc7b6e79e8d3a5cd025f3' 
  AND token = '6W3EGVvYHcXG9Ic9M3gwW5pC0qQVer+ZLPEhS8/2+No=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}