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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f34c36f7c5b6519ea5e465bf3cceb61fabe83f224d00b2eb4e4d9551e1f9b04' 
  AND token = 'A/YaPv61PGPA6K5wOBDKc0/s5A89+OeiYqC9clvEVTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}