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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5ee2c82ad1c80fdeaf7128e4908a27a899eb17681839e581d29d9f5bc836319' 
  AND token = '0KTcMLPvuQWYqcPfE+WtgwVKYP8kPJV82hpjgalXyKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}