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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4451275808a56adf58a5945b43e2d267423c1291fc9442af1b1e2a7386b0267b' 
  AND token = 'x64j40y6AeQ3LOclxBtOV90RhI9AkB6crEkBvp4WI/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}