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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bd2354c90d61b2a21d908ddec122c623df0a2f86726d6da6e15837ee417cbc8' 
  AND token = 'Tit/4pyPems9iOioGFFHxRe1pTRC+v6WmwAOIT3Yf7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}