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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15146b8d43783752e0c4f4d105eaec7db9af5356e4d6510a9e9e4dac3c6a2a21' 
  AND token = 'drdVjtatCbEhsbVNoO36ypBb4U71aUVH640QgIdXD8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}