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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c822d6d094012266a8b868a7592ba61ef6d280fa1d872f80dce8a920efd7ebc' 
  AND token = '5MC3esBU+bUYPjrn4mF3n93uoBDTxtL3jj449U0Mus4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}