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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc716251cba637f18fba51ac396ce5d3d2d03362fefff511ac7d3705d94c9d27' 
  AND token = 'AoD7WK7BbjRVtB2wuTi4nVSIYuigkMcDkEiLY38jjtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}