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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0106a2049ff34a78874c279a9a9f5fc1bea802621984b355da26f03ee6c92326' 
  AND token = 'Bw4HN1dAM+ueFoS61enFjtNf9jGZxqHL9LN9Py+LouQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}