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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '223cd7cac758db4c28a679543203d03cdf32f2d7d56c091dd7b2636e200db967' 
  AND token = 'dWnL8NBITOtIy/Vms6a/GR5UPRuG75SU8BiyLwvvYOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}