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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0b89cb9925ce02e5dfd83e143e9c406feb56e1d8a8de07d1f41876288a7cdfe' 
  AND token = 'JjOlSWwTPsP/S/T2uas0AQ8alyITpDu9ky7kqdr2BSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}