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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2bf04a500fd30ec041b9ce1de9b772d7b591938e14e7c8107e5981b276f7c90' 
  AND token = 'FEw9tzjlTZxAP4QR9/bfuYhAY3AcXA1A4GaZNBeE2jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}