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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '768590ef734d08a4709e794149dc8f56a70b3633d00010d7a6c8d9ded8a012ff' 
  AND token = 'n01+c2NJF+d8bJbJ6YDTU+hf85ji4Hn7Eyyg39Axq5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}