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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd569b29973bdaa8d2a699e5b513af923376a58b317d989650d3213f0a3b36a2a' 
  AND token = 'RvM6A1gWyweIUlmGcT6pVQ32SgLUeQzKGManq7thLIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}