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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fb59ce45eb45a7cc5d0838ea9336c9bdb8c1b97105136c7e8977422bce24a8c' 
  AND token = 'B1YQ3FPboMuZI029kZ/4U38FAwy9raYjY10JYlXFJz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}