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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654f9e5a7921b8cb6ced7e9608e4752572f42e7531c89209de0a504cadf29a3e' 
  AND token = 'gRtNZUMz/EULU13XTCtCjOpFq70BHq5KSHqPinRta2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}